I don't have advice on how to make it right.

Also it would be very difficult to say if your wife has schizophrenia. There is a lot to it, it's a very complex thing. And from what you've described it doesn't sound like it to me, but you have only described a little. There is so much to schizophrenia, and multiple types as well.

To me it sounds more like the kid who has lived with extremely strict parents their whole life, so when they get to college they go nuts with their freedom. I've seen it happen many times. I knew a girl in high school who was a perfect, straight A girl. Perfect behavior. Sweet as could be. Super good girl girl. But her parents kept her under lock down, except to go to church group. She moved to college and within 6 months had been failing all of her classes, dropped out, was not only taking drugs but dating a drug dealer and prosituting herself out, and the last time I saw her she looked like a shadow of herself. It scared me and I was never able to contact her again. Sometimes I wonder if she's okay now.