You may have just answered my question. My friend out of the blue during the course of a lovely day, just wanted to go home and go to bed. He said he had a build up of sudden anxiety. And it occured just as we stepped outside after dinner. He asked me to bring him home at 6:45 and he was ready for bed. He did this yesterday too. by 5:30 p.m. he was in bed and didn't get up till 10 this morning. He is going through a med adjustment at the same time as a season change. He is allowing me to track his moods and for the past three weeks he's been distant and depressed. I try my best to help in what ever way I can without being invasive to his privacy. I see him most days of the week and on the days I don't see him, we try to at least text a few words. Thank you for pointing this out..