Confused, lifestyle changes are hugely important, but so correctly dosed drugs, including THC and alcohol. Today, a little wine helped me do what I loathe and usually negelct doing: mop my kitchen floor. Hoorah! I will now try doing it weekly. And I mean, just a tiny bit of wine. So in my 6 years with psychiatry what I have learned is the importance of dosing. And beyong psychiatry, too. Alcohol in high doses is toxic. In moderate, therapeutic doses it is hugely helpful: it prevents a host of diseases and is a must if you plan to live a long life actively and independently. Sure, there are people who cannot stop at the therapeutic dose and such people should not drink at all, but people like me who can dose properly and who do not experience untoward drug interactions should consume alcohol for their long-term health. I have learned to dose marijuana through trial and error and now consume very very little without absolutely any psychodelic effect. My doctors learned to dose Lithium through trial and error - I was at a dose that was toxic but now am at low-to-medium dose that is not toxic but just helpful. I take the smallest possible dose of Prozac (no wonder I experience no side effects). The smallest possible dose of Amitriptyline (likewise, no side effects which is not surprising at this low dose). Started on a very small dose of Topamax and we will see if it works, so far no side effects. Geodon - you all know what it did to me at high doses but at a medium dose I am fine. So it all depends on the dose. But there are absolutely pernicious medications which give side effects at any dose - Zyprexa with weight and Depakote with tremor have been like that for me. Clearly I am never going back to those, ever.