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It depends on the antidepressant. Personally I've found ziprasidone to enhance caffeine's effects the most, giving you the most lift in mood, but all antidepressants subtly effect caffeine to a small degree I've found. Some worse, others better.
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Dx: Atypical depression/anxiety/OCD
Old Rx: 250 mg clomipramine, 160 mg ziprasidone, 90 mg mirtazapine
New Rx: 20 mg aripiprazole, 200 mg disulfiram
New Rx 2: 30 mg tranylcypromine
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