yes.
if it has something to do with rearranging neuroanatomy such as enabling null neuropathways to crucial segments of the brain, it can work to be beneficial.. it is how savants, become, savants.. only speculating though.

if we are talking about a drug that induces precipitated effects, it's the instant gratification that can lead to negative aspects of it.

fondling with your mental aptitude is need not, but if you get given the chance, then it is something i would pursue personally.

what i would find amusing is giving a placebo to a number of people then watching think they've become smarter but they actually subconsciously enabled their ideometre, making them feel and act more creative and logical.. tricking your brain into thinking it is running a circuit of acquired intellectuality.. well, that's only if you aren't a skeptic. tricking yourself into believing in something can be stronger than any potent drug there is itself.