You know that external events can trigger depression. It doesn't seem like you've gotten along with your boyfriend for a while now. I could be totally wrong, but I've seen you complain about him before.

If you're taking SUPER high dosages of any medication, you should taper. I'm was taking 50 mg of seroquel and it will take me 2 months to taper off it. (Incredibly slow taper!!!) Remember drug withdrawals can manifest themselves as psychotic/depressive symptoms so stay close to your support team. (And PC)

I hope things get better for you.