In addition to those things that people have written about, I think vitamin D3 is very important. Unless people get a lot of sunlight. This is true especially in the winter. I know am taking 4,000 mgs of vitamin D. I was taking only 1,000 mg in the summer. I have a friend who got Vitamin D3 injection, or maybe it was that she took vitamin D2 liquid, from a naturopath. She said it was like turning on a lightbulb. The intense depression lifted. I am taking EPADHA also. Both the suppliments I wrote about are being increasingly recommended by MDs

As for B12, it saved me. I was having ongoing panic attacks. Nothing was helping. I was told that people who have digestive problems do not absorb vitamin B12 easily. So I got B12 cream. The painc attacks stopped. And I have never again had one again.