If you are unhappy in your marriage, it could be stressing you out enough to cause you constant anxiety and sensitivity. This stress could be enough for you to exhibit lack of sleep/eating issues/generalized anxiety. Meds can help the symptoms, but they cannot help the situation you're in. Chances are if you're unhappy in your marriage, you will still feel unhappy on the medication at any dose because you're just unhappy in general. The medication may give you the motivation to get out of bed and go to work, but it's not fulfilling that loneliness of being in a bad relationship and wanting human interaction/better emotional/sexual connection with another being.

I'm a huge believer that our emotional well being affects our ability to cope.