Interesting that those in this thread who have answered no or not really and see their issues in quite a positive or accepting light, I get the impression can do so and would choose to hold onto what's familiar about them all these years because they fundamentally like and/or accept themselves.
For me I can't stand the way I am because of my issues and have no sense of self as ok or likeable or acceptable neither to others nor to me, and so a magic pill would be wonderful if it could get rid of all the negative stuff that is messing me up and leave me with a sense of self that would allow me to feel safe inside my own head.
I really envy those who like and accept themselves, I really wish I could feel ok about being me

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Bring on the magic pill I say