I took Concerta for awhile until I started a new drug that had bad interactions with it. I took it because I was always tired and just sat, staring all day. I looked up the indications for it in my PDR. For FDA labeled indications: ADHD, narcolepsy; for non-FDA labeled indications: fatigue (that's me), incoordination, impaired cognition, shivering, TBI. It does not include anxiety or depression as indications for use.