That is what happened to me I hit 400 but the anger was all coming back. I loved lithium but the side effects for me were to much but I would definitely give it a try. I did not gain any weight I just peed all the time so it kept me up all night and my skin broke out in horrible cystic acne. I was already prone to this acne so I think it just aggravated it. it really mellowed me out. I am now trying tegretol.