Do you typically have sinus problems? Are you on any medications? I have found out that the combination of ongoing sinus problems, GI problems and starting psych meds; I can not even have one drink. I used to enjoy wine occasionally with friends and now if I have a drink or 2, I am up the whole night with sinus congestion so bad I am sick to my stomach. This also included diarrhea. I think sometimes our body chemistry and changes make it to we're we can't drink even a drink anymore.