(this is CnP from an RA discussion board)

I wanted to see if this was common, or had happened to anyone else. I'm currently on mtx 20mg weekly (8 tabs), IB 800 4x daily, Enbrel (50mg sub q injection) 1x weekly, Plaquenil (2 200mg tab) 1x a day. I occasionally, the least is 1.5 weeks apart--most is 3x in a week, get a deep pain in my bone. Its nowhere near the joint, and the only way I've been able to describe it to people who haven't had it is a really bad charley horse, inside your bone. It comes suddenly and lasts from 10-60 minutes. When its in my leg I can't walk or put any pressure on the affected leg until it passes. The pain is very intense, the last time I had one (approx 8 days ago) I fell against the wall and grit my teeth so hard I broke a tooth.

Has anyone experienced this?

I've tried calling my rheumatologist, but have so far only gotten voice mail. I'm hoping they call me back today before 5. Not overly hopeful as its 4:30 right now. (no word until next week, its after 5 now)

I've reread all the info on the meds I'm on and nothing similar is mentioned, nothing in the RA info I've looked at either, unless I somehow missed it.

I'm posting this to see if someone has experienced or even heard of it before. Sorry for the CnP, but its too long to type up again!