I hated Prozac and Zoloft. They made my depression and ocd worse. I've also tried wellbutrin xl and remeron. I'm on remeron right now. I don't know how expensive it is but it's kind of like a sedative, I take it at night and it puts me to sleep. Upside, I'm not anxious or depressed at all, downside, it makes me hungry and I've gained ten pounds. It's like the pill form of weed.