Personally, I decided to quit drinking after I noticed even one glass of wine can spark a depressive episode, or make an already existing one worse. Combine that with meds that don't mix well with alcohol, and I figure drinking is a bad idea.
Plus, my partner is an alcoholic. She's been sober for over 6 years now, and I *don't* want to be responsible for her relapsing!
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http://www.queermentalhealth.org/ - Resource and support site for LGBTQ people and their partners