I'm on Wellbutrin as well, and Abilify. But I don't think any drugs are designed where you can "pop" one when you are feeling in a mood, as they take a while to kick in. But who knows maybe some people take them like that. They are designed to be daily. I take Abilify to prevent mania, as I was given it first when I was hospitalized the 2nd time. So far two years and no mania. I know what my trigger is now though, too. Wellbutrin is a good anti depressant, but you can read another recent thread or two that shows many people get manic on it. So you should have a good mood stabilizer or anti psychotic ready to fend off the mania in your bloodstream as well. I think most psychiatrists prescribe something to prevent lows and something to prevent highs, to try to sandwich us into the normalcy range. I don't cycle so I'm easy to deal with though I think, tending towards depression all the time. Which the Rx's I take help.