St. John's Wort only works for mild to possibly moderate depression. Also, you cannot mix SJW with certain meds, so you would want to make sure there are no interactions. As well as it causes photo-sensitivity, so you have to keep that in mind.

I think it's all a personal thing. Some people tolerate certain meds better than others. The only way you will know is by trial and error. For me SSRI's seem to give me nonrelenting migraines...so I can feel your issue there.

G'luck, on whatever you decide to do. If you do try it could you post to let me know how it worked for you.
Thanks, hugs, Lisa.