I was told not to flush but return to the pharmacy that would dispose of the pills properly. But I have not done it. I actually gave some to my p-doc friend who works in government mental health in Moscow, where there are no stringent federal rules, so he could give to patients who are struggling to afford drugs. He took everything I had at that time except for Benzos, which he does not like in general. Took all my left-over Trazodone, and something else. So when he visits in the fall, I will give him Abilify and Geodon and Topamax, all combined costing way over a thousand of dollars! At least someone will benefit from them because I, like you, just feel bad wasting expensive things.