I used to self-medicate A LOT. I drugged and drank for years. I would drink daily for imagined relief from anxiety, mood and paranoia. I would smoke large amounts of cannabis and for instant gratification ingest MDMA. I was on very little medication at the time, yet did not even care about the side effects.

I do not recommend self-medicating, it causes more harm than good in the long run. You may find instant relief, but both alcohol and cannabis are depressants and can worsen depressive symptoms. It's also extremely important that you are honest with your doctor about how much you are self-medicating and with what. For years I woud tell my doctor about the alcohol and drugs I used but was never honest about how MUCH and how OFTEN I used them.
It's important for your doc to know and that your current regime is not providing relief...

I stopped self-medicating years ago and got myself into a program of recovery for alcoholism. Again, if self-medicating becomes a habit it can progress, and quickly. I do not recommend it, despite the illusioned 'relief' it brings. I have found much more relief in a straight-edge lifestyle with healthy eating habits and lots of exercise (I don't use coffee either) along with honest and open discussions with my doctor about day to day struggles. I only share my experience in that it may help someone.

I hope you find some relief soon. Best wishes