Part of my depression has to do with loneliness. I work fairly isolated and then I go home to an empty apartment. I am an introvert and don't like being around a lot of people, but a good friend or two would be nice. Weekends are hardest because I can often spend the entire time alone in my apartment, not wanting to go out and not having any place to go anyway. And a lot of people here seem to take the weekends off from the forums too.