Yes. I take 300 per day of the Lamictal. It gave me absolutely excruciating headaches. I take Topamax to stop the headaches and it has been very effect with eliminating them (but topamax has its own very significant set of side effects- I'm just willing to put up with them.) There are a number of medication available to deal with the headaches if it ends up being a long-term problem but you find the lamictal is otherwise doing the job. Ask your pdoc about it.