I wouldn't check your medication. Just based on the fact that you can't be sure what's going to happen to your luggage. It's one thing to have your luggage lost and need to get replacement clothes, another to replace medications. Also don't pack valuables in your luggage becuase things get stolen.
Last time I few domestically (in the US) I put my medications in a pill box in my purse and no one even blinked twice about it.
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