Been taking Seroquel for a few years now. No wieght gain. It does help me to sleep! And when I am having a bad day emotionally/mentaly, I am greatful cause it does help! The drawback for me is the sedation part. I wake up in the morning sedated sometimes for hours. But my PDoc and I are looking at why that is. Same days are fine, others, not so much. It is an individual experience. Can you just give it a "trial run" for a month to see? Good luck to you, I hope you find what you need!