I agree that your brother should see a therapist for sure...a bunch of these meds do have crazy side effects, and he seems awfully young to deal with those.

Cymbalta messed with my short-term memory (I was prescribed it for depression)...other people had to remind me if something happened THAT day or the day before, etc. I will also say that I am in the 1% of the odd side effects group of everything, but since you asked, I thought it was worth mentioning. It totally freaked me out, but I was fine once I got off of it. The side effect showed up after like 3 days of being on a low dose, titrating slowly.

I wish your brother the best and hope he can get help without meds.