Don't have those but do have cerebral palsy which is simular as in lack of muscle strength, maving many muscle spasms through out the day and nights and so on. I believe any physical health problems can and do cause depression to get worse. If a person isn't feeling their best physically that is going to reflect on how they are feeling mentally too. I know I get irritable and so on on the days that I can hardly walk and have to rely on my crutches and brace to keep me from hitting the ground. Im a get up and go type person and not being able to go when, where and how far I want definately makes me want to just pack it all in somedays.

As for injecting things in the brain a friend of mine that has MS says the injections actually help her because it is putting back into the brain the chemicals and so on that the desease takes away basically helping to slow down the desease and keep her walking, talking and feeling physically and emotionally at her best that she can be with this desease.