I know someone who had Ketamine and it didn't work. I think there must be some
serious reason for not using it unless the situation regarding depression is virtually hopeless; then it might be helpful. It is given by injection only, I think--I could be
wrong on that, but I believe she was hospitalized for treatment by injections. Very serious venture she indicated--not done locally; she had to travel a long distance to reach a hospital that would take her based on her history, etc.,with depression.