The Clinical trials having been going on for years. Ketamine works on the glutamate system in the brain. This is an area of the brain that prior to ketamine trails was not looked at.

Severe depression and bipolar depression are lifted within hours. They think this is the sweet spot in the brain. Antidepressants take so long because they have to go through chains and chains of chemical reactions before they hit the glutamate system.

Also, ketamine and the new drugs based on it do not cause mania or cycling.

Some people are caught up on Ketamine as the street drug. That is a shame. In clinical trials and Outpatient Surgical centers that offer it, use a incredibly small dose of it. As I said in my other post, you are monitored the whole time. I wish I had more money the results are miraculous.

They also have been doing ketamine infusions for certain pain syndromes for many years. They do them in the place where I had my infusions.

There is a drug Rilutek that has been around for a long time. It is for Lou Gehrig's disease. It is being used off label for depression and bipolar depression.
It also works on the Glutamate system in the brain. But it is much weaker. They are doing clinical trails on it also.

The supplement NAC, works on the glutamate system also. It must go through more chemical reactions to reach there. It to is much weaker than ketamine.

I have been researching ketamine for about 5 years. This year it hit all the major news media. Like I said before it is not Ketamine itself but the research breakthroughs that have come from it that will be revolutionary.

It won't be too long before the new drug based on hitting the Glutamate System will be available to us.

Have had Ketamine Infusions, I know this new drug will relieve much suffering and prevent many suicides.