I've been treated with Amitriptyline for many years now due to two fractured lumbar vertebrae and cervical compression (thrown head first into walls tends to do that). I have had to increase my dosage to silly amounts just to get any result out of it at all. I was prescribed it for two reasons - due to the spinal injuries I get pins and needles or burning sensations in my feet, and... I didn't sleep. I have been wondering about long term effects myself, since for the first time in my life, my memory has begun to suffer after I resumed taking it after a hiatus of 8 years. To get any effect from it at all, I need 200mg at night. It won't be long before that will cease to do any good either.

I very much miss having my near photographic memory.