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That's easily understandable; drugs were probably in use thousands of years ago or as early as humans were able to discover that certain plants offered "benefits".

Even the knowledge now that alcoholism may have a genetic inherited component
confirms your statement. (And that applies to other mental problems, as well; I
recognize a genetic component in my illness.)

Isn't it true that scientists have (to some extent) relied on the knowledge and application of drug use in third world countries to produce some of the current medications in use now in the pharmaceutical industries?

It's big, big business.