I gained a lot of weight on Pristiq and got off of it about a yr and a half ago - started Prozac, then Lexapro - and weight just keeps on steadily going up. GRRR... When I was on Wellbutrin alone I was 117 lbs.... now I'm at 150. Really thinking of seeing if I can go back to WB and get off Lexapro. Don't know if that will even help.