I can't give you any advice on the medication side of things, but perhaps if they are not working then you should try other things as well.

I was had anxiety problems and depression a few years ago and I was referred to a mindfulness cognitive behaviour therapy course and it has changed my life no end. It has helped me make peace with the world and all the bad things that happened to cause my issues in the first place, and I would even say I am happy now. Maybe not laugh out loud happy but happy enough with who and where I am. I think it could help you too...

Good luck with whatever path you choose.