I was on Wellbutrin a couple winters ago (it was added to my other meds for bp) when I fell into a depression. It worked really well. I was able to get off it in the spring (have some SAD). I didn't have any side effects.

Now, a friend of mine tried Wellbutin because Zoloft was blunting her sexual feelings & she had a really bad reaction. She "felt like she was going crazy" within 4 days & had a panic attack. She ran back to the Zoloft--sex be damned.--Suzy