[QUOTE=Jan1212;3010371]topimax increases chance of acidity in your body called metabolic acidosis, it lowers bicarb, the "base" of your body, which can also aggravate renal impairment
When you got your bloodwork, did you tell them your current meds? I don't know when you went, but what did they say? I would also taper, lower, or even stop topimax . It might be secondary to the med, so it should resolve

Metabolic acidosis requires monitoring at a clinic/hospital, because it involves various electrolytes. The only thing I can think of that your body can do on its own is hyperventilate, to give off that excess acidic carbon o2, making your body more alkali. sit upright to help your lungs out.

Honestly, he showd me but I don't remember, I just knew he said it was worse. I have tapered of the topiramate altogether and my breathing has improved. Strange thing is, this last appointment was over two weeks ago, I suddenly got a phone call early Friday morning from one of the nurses( I was driving through georgia on my way to florida from central mass on a family vacation) she told me he wanted me to cut my lisinopril in half and test my blood pressure for two weeks. When I asked her why, all she said was your blood test came back abnormal. Which still left me confused, why over two weeks later? My blood pressure was trending hight even before the tpiramate and more after( last day on it was the 11th) I went out and bought a bp machine to test as he's asked and noticed its been on the low side now.(100-110 over 65-75). I'm confused, I've been working hard to drink more but have lost some ground down here park hopping everyday. I'm also on aplenzin, hydrochlorothiazide, lisinopril and very recently off topiramate. Thank you