I've been on Viibryd for about 3-4 weeks now (and also switched from Lexapro since it pooped out). At first the nausea was pretty bad (though it was nothing compared to the nausea from Trazodone), but now I experience absolutely none, even if I take it without food. I'm liking it a lot so far. I feel like it's definitely helping, and I'm now at the full 40mg.