My story is similar... 12 years on pills (zoloft, serzone, wellbutrin, effexor...) leading to increasingly severe depression and anxiety no longer responsive to meds. Finally realized I had to find alternatives or I was going down...

Here is what pulled me out of my crisis and helped me through the worst of my withdrawal:

--EMDR therapy. This is a technology-aided talk therapy backed by solid research. It is much more scripted and to the point than traditional talk therapy--the therapist knows exactly what cues and responses she is looking for to "defuse" one's issues. My EMDR therapist was great. I felt better after only a few sessions, and a full year of sessions ended with my severe depression and severe social anxiety in remission. The word on the street among EMDR therapists is that antidepressants tend to get in the way of true recovery. So my EMDR therapist was very supportive of my tapering off medication. I do not think I could have done it without her.

--A sound and light neurotherapy system. Another research-backed alternative to medication. I got the top-rated system on Amazon.com. It was a HUGE help to me in reducing anxiety and getting to sleep (sleeping pills never worked for me and were a suicide hazard).

--neurofeedback. Another solid research-backed alternative. Can be expensive. In my view, it was worth it. This may be the best of the bunch, frankly, but I did not find this method until I was already through the worst of my crisis.

I also added exercise (early morning in natural light preferred) and certain supplements (Vitamin D, B12, Omega 3 (EPA and DHA--I use a vegan source to avoid the chemical instability problems of fish oil)). I have since added choline and selenium, just for fun.

Good luck.