I am slowly working my way off Paxil and onto Cymbalta. So far, it is helping quite a bit. The theraputic pain dosage is at 60 mg. I am at 50mg at this point, not quite off the Paxil.

The big drawback for me about the Cymbalta is the price. There is no generic yet. My insurance rates it a tier 3 med, which means that it it very expensive.... I pay about $100/month out of pocket, and they cover about $150.

I don't know anything about Lexapro. I do know that Cymbalta is an SSRI and Norepinephrine-something-or-other drug.