prozac did eventually poop out on me after 3 years, it took 3 more trails to find another med to help and no half killl me. I tried about 10 years later to get back on it but my body was haveing none of it and it made me really sick to the point it was put on my med records no prozac. i was only on 20mg the 3 years i was on started straight at 20mg an stayed there has it failed i tried 40mg but reolised my time with prozac was over.