I gained 20 lbs. in six weeks on Zyprexa. My diabetes also went completely out of control, and I honestly thought I was going to die soon. The drug does a great job of tamping down mania and evening out moods, but I had to go off of it too. The good news is, I lost every ounce of the Zyprexa weight and then some!

Whatever you do, though, do NOT quit without your pdoc's knowledge. S/he will want you to taper off because you don't want withdrawal symptoms, and you probably need another AP. I'm on Geodon now, which is weight-neutral (in fact, I've lost a little more weight in recent weeks)...you might want to ask your doctor about it.