Lamotrigine wreaked havoc on my cognitive abilities. My short term memory was especially bad. It was difficult to learn new stuff and apply old stuff to new situations. I kept transposing numbers far more than usual - unacceptable since I worked in accounting. My ability to focus was gone. It was like I knew that 2 + 2 = 4, but I didn't understand why and couldn't move on from there. So frustrating!

I was taking to 150 or 200 mg at the time. Now I'm down to 75 mg, and my cognition has improved a lot. I did need to add Seroquel and Prozac to offset the lower dose of lamotrigine. So far that cocktail is working for me.

My pdoc said that lamotrigine is known for causing cognitive problems at dosages of 100 mg or more. I know you're only taking 50 mg, but perhaps you're ultra-sensitive to it. Then again maybe not. It varies so much from person to person!