I have probably tried about 20 and most not SSRIs as my body has the same bad reaction to them. I tried Remeron, too...first night I slept til 5 pm the next day (I was so out of it even then), and my pdoc said that side effect would probably only get 20% better over time. Pffft, yeah, I don't think that's going to work.

He wanted me to try Effexor as the last option he had the last appt I had but I just haven't as I am the 1 or 2% who gets the crazy side effects with these meds and Effexor seemed too scary to mess with.

So I take Klonopin, which never has helped with my anxiety, it just helps me with my nightmares and I am able to sleep (sometimes...my insomnia can also "beat" the Klonopin some nights, too). As for the depression...guess I just stay depressed.

Good luck to you, I hope you find the right med/med combo, and soon.