I was put on 300 mgs of Seroquel to start with and over time the dosage was repeatedly halved. I'm now taking 25 mgs before bed. I was totally out of it when I was taking the original dose, especially when it was combined with Ambien. I was sleepwalking and sleepeating without realizing it. The 25 mgs makes it easy for me to fall asleep and I sleep solid throughout the night. I haven't taken Ambien for a very long time and don't anticipate any need to.