I have treatment resistant ultradian cycling/mixed state, accompanied by migraines. The amino acid, taurine, which acts like an anti-convulsant and is neuro inhibitory, works for me when I'm extremely manic. I start with 3000mgs and if it doesn't slow me down within a couple of hours, I'll take 5000mgs and sometimes I need to take up to 9000mg. The downside is that it does induce depression(like you, I also take Klonopin), leave you draggy for a couple of days and might constipate you but it does take the wind out of the mania. I'm not a doctor, pharmacist or medical professional of any kind, just an amateur psychopharmacologist.