Two of my p-docs have said that the worst thing you can do is to miss the time when you naturally get sleepy and stay too late, because it is then difficult to get sleepy again. So if you know that it takes 45 mins between taking Seroquel and being semicomatose, then determine when you want to be in bed, take Seroquel 45 mins before that time, and then do something quiet for those 45 minutes, and then just turn the lights out.

I will turn the lights out in 10 minutes myself to offer you moral support! I take the sleep meds at 10 and turn the lights out at 11. It works.