Myself made some good points, no matter how crappy the answer you got felt. My Grandmother was Manic and my mother dealt with her ups and downs all the time. She until the day she died thought nothing was wrong with her. And she was on Lithium, but even then would not take it as instructed and would drink. She would call my mom in the middle of the night and tell her how horrible of a child she was, and bring up how she wore certain shoes when she was 5 and wasnt suppose to, and was a bad child for that and so on. Other days she was high as a kite and would go down to the local restraunt and dance on the tables. I kid you not, she was almost 70 at the time. She died a few years later, going through all this turmoil, missing all the holidays and gatherings. And nothing could be said or done to make her change, or stick to her treatment. I wish I could give you some positive instruction on how to handle this? But as Myself pointed out, the only thing you can do at this time is be her daughter, and hopefully someday she will finally see that something is wrong. At that point you can step in and be her support. Of course maybe a doctor would tell you different, this is just from personal experience. I wish you all the best!