So far I've only had to stop two (Trazedone and Seroquel). Trazedone because it was making me too stoned to function and screwing with my blood pressure, Seroquel because it was making me start to gain weight fast.

I'd like to switch or discontinue Zoloft, because I still get deep depressions and I'm afraid it may have had a role to play in my being in mania for a while.