You probably only have to close the browser window itself and then restart it, but if you have the patience to reboot that way you can be sure everything reloads fresh (that's what I usually do when I'm troubleshooting).

A full browser cache can cause other problems so this is worth a try: Again in Tools => Internet Options => "General" tab... in the middle it says "Temporary Internet Files" and there is a button there that says "Delete Files".

Those files are just "convenience" files... everytime you view a web page with graphics, when the browser opens the graphics to display them it also puts a copy of the graphic file in a temporary "cache" folder on your computer... that way if/when you go to that same web page it can open the file from your computer instead of downloading it again, so the page can load faster. It doesn't have anything to do with any of the program files or important stuff. At worst all of your websites will take a little longer to load the first time you visit them after performing this step.

Sometimes if there are too many files "cached" it can cause some problems.

So click the "delete files" button under "Temporary Internet Files" and wait for it to finish, it may take a few minutes or even longer. When it is done, restart (if you want to completely reboot that's OK) and then see if anything has improved.

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--http://www.idexter.com