I am a little new to this, but I figured it doesn't hurt to ask. For years I thought I just had depression, and now my new pdoc thinks I am manic. I have recently switched from an anti-depressant to Depakote. I don't think I have any of the happy side effects of mania but the irritability and depression are definitely there. Does anyone have a good method for getting yourself to calm down and focus during the day? I am trying to get used to the Rx switch, but it isn't easy somedays to turn my head off. I could use any suggestions.