I too suffered from terrible PMDD and felt insane a few days prior to my cycle and during my cycle...... it got to the point that I was classified clinically depressed with suicide tendencies with my PMDD and the only thing that saved me and my life was Celexa. I started out on 20 mg once a day, but now I take 20 mg twice a day - 1 pill in the morning and 1 pill at night..... I will probably have to remain on Celexa until well after I go through menopause and the emotional roller coaster of hormones have stopped. Maybe you should talked to your primary doctor or your GYN about talking Celexa?