thank you for taking time to reply. i did try a therapist and he said was suffering from selig syndrome aka learned helplessness. not sure i agree. i cannot afford therapy at the moment. when im well im a real trooper and tryer and always positive. this is first time depression has been uncontrollable. i took seroquel last night as my thoughts were all over the place and was anxious. i had stopped them because of tiredness. feel a bit calmer today but couldnt stay awake! i wonder if loneliness is part of depression. I've felt it since childhood a lot, even in company of others. its like a big empty space that can rarely feel filled. does any one else feel this?