I'm on Wellbutrin XL 150mg twice a day. I used to smoke 5-6 ciggies a day. It stopped me smoking. Other people might give different effects like down to 3-4 ciggies from a pack or something. If you're depressed, then double rewards. Some people can't handle the side effects. A different form not the XL(zyban)was used for that purpose, but side effects caused some headlines.